The rat and mouse aerosol exposure chamber (whole-body exposure system) can atomize drugs, allergens, or other mixtures into extremely fine aerosol suspended particles and send them into the chamber where the animals are placed. The animals are exposed to it for the predetermined time in the experiment to complete the sensitization and stimulation process required for animal modeling; It can also be used as a whole body exposure system to expose animals to the whole body;

(Yuyan Instrument Company can customize special gas poisoning boxes according to customer needs, such as carbon dioxide control boxes, sulfur dioxide poisoning boxes, carbon monoxide poisoning boxes, oxygen concentration control boxes, etc. Welcome to inquire by phone)

There are various sizes and specifications of exposed boxes to choose from, and customization can also be made according to needs:

Note: The actual capacity may vary depending on the age and weight of the animals. According to the characteristics of the drug, nebulization and exposure devices are best used in biosafety cabinets.

Exposure box model: S2

The main characteristics of the whole-body exposure system are:

·Simultaneously modeling multiple animals saves time and has good consistency.

·According to relevant literature, taking OVA sensitization as an example, modeling with nebulization method requires less time than abdominal injection method.

·The integrated controller also has timer function, atomization parameter setting, and 0-5LPM bias air supply system.

·Biased air supply can provide fresh air for animals inside the box during a prolonged sensitization process, while maintaining the temperature and humidity inside the box from being too high.

·We offer two types of atomizing heads with particle diameters of 2.5-4 μ m and 4-6 μ m for selection.

Please choose the appropriate exposure box size based on the type and quantity of experimental animals exposed.

Can be used with Aerogen Pro atomizer and Aerogen Solo atomizer;

The atomizer adopts palladium alloy vibrating grid technology, with a central orifice plate diameter of 5mm and 1000 precision formed micropores evenly distributed. It vibrates 128000 times per second, forming aerosol particle droplets that are very conducive to sedimentation into the lungs.

model: Aerogen Pro

Main advantages of the product:

·Both short-term and long-term experiments can ensure excellent and consistent output;
·Low atomization dose;
·The particle size distribution and particle object concentration have a high degree of repeatability;
·Medication can be filled at any time, and an automatic injection pump can also be used to add medication;
·Corrosion resistant shell design, durable and long-lasting;
·Highly integrated and compact in size;
·Easy to operate, no need for complex training work;

Main parameters of atomizing head：
·Small: Volume Median Diameter(VMD)
·Atomization rate:> 0.1mL/min
·Particle size: VMD (volume median diameter) ranges from 2.5 μ m to 4.0 μ m
·Drug residual amount:< 0.1mL

·Liquid atomized aerosols have many applications in scientific research, drug development, and quality testing;

Schematic diagram of atomizer connection:

Particle size distribution of atomized particles:

According to your needs, you can also choose the BGI Collison aerosol generator from the United States

MRE type Collison aerosol generator is a flat bottom spray designed by Microbiological Research Establishment. It has a variety of models including 1 nozzle, 3 nozzles and 6 nozzles. 3 nozzles are the most commonly used model.

The following image shows the animals exposed to the Collison aerosol generator with an animal poisoning chamber and compression pump

The specifications and dimensions of animal poisoning boxes can be customized according to customer needs:

We can also recommend more suitable atomization poisoning combination schemes based on laboratory needs. Please call us for consultation.

According to experimental requirements, you may need a dust aerosol generator, aerosol concentration measuring instrument, and particulate matter concentration measuring instrument:

Dust aerosol generator, capable of atomizing dust and producing stable dust aerosols

Aerosol concentration measuring instrument, used for real-time measurement of aerosol concentration in exposed environments

Particle concentration measuring instrument, used for real-time measurement of particle concentration in exposed environments

Partial application literature:
[1] Wang Ying The effects of bisphenol A exposure during pregnancy and lactation on hippocampal function in neonatal rats [D]. China Medical University, 2021. DOI: 10.27652/d.cnki.gzyku.2021.000130
[2] Ji Xiaotong PM_ (2.5) inhalation exposure induces lung injury and its molecular mechanism [D]. Shanxi University, 2019
[3] Ku Tingting Study on neurotoxicity induced by PM_ (2.5) exposure and its related molecular mechanisms [D]. Shanxi University, 2017
[4] Ma Yongchang Study on the effect and mechanism of ROS scavenging nanoparticles in the treatment of neutrophil asthma [D]. PLA Army Military Medical University, 2021. DOI: 10.27001/d.cnki.gtjyu.2021.000097

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